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Effects of huperzine A on secretion of nerve growth factor in cultured rat cortical astrocytes and neurite outgrowth in rat PC12 cells

✍ Scribed by Li-li TANG; Rui WANG; Xi-can TANG


Book ID
111354867
Publisher
Nature Publishing Group
Year
2005
Tongue
Chinese
Weight
128 KB
Volume
26
Category
Article
ISSN
1671-4083

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## Abstract NRAGE, also denominated as MAGE‐D1 or Dlxin‐1, is firstly identified as a molecule interacting with NGF low affinity receptor p75NTR. It facilitates cell cycle arrest and NGF‐dependent neuronal apoptosis. Here we report that NRAGE is downregulated while p75NTR is upregulated during the