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Effects of human papillomavirus type-specific antisense oligonucleotides on cervical cancer cells containing papillomavirus type 16

✍ Scribed by Y. F. Wong; T. K. H. Chung; T. H. Cheung; S. K. Lam; A. M. Z. Chang

Book ID
112969463
Publisher
Springer US
Year
1994
Tongue
English
Weight
194 KB
Volume
11
Category
Article
ISSN
1357-0560

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Human papillomavirus (HPV) type 16 DNA is frequent in invasive cervical cancers. Among 43 patients with invasive cervical cancer, HPV-16-positive tumors spread to the parametrial and pelvic lymph nodes significantly more often than did HPV-16-negative tumors ( P < 0.05). Demonstration of HPV-16 DNA