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Effects of histone deacetylase inhibitor FR901228 on the expression level of telomerase reverse transcriptase in oral cancer

✍ Scribed by Jun Murakami; Jun-ichi Asaumi; Noriko Kawai; Hidetsugu Tsujigiwa; Yoshinobu Yanagi; Hitoshi Nagatsuka; Tetsuyoshi Inoue; Susumu Kokeguchi; Shoji Kawasaki; Masahiro Kuroda; Noriaki Tanaka; Nagahide Matsubara; Kanji Kishi


Publisher
Springer
Year
2005
Tongue
English
Weight
521 KB
Volume
56
Category
Article
ISSN
0344-5704

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Antiproliferative effects of the histone
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## Abstract FR901228 is a novel histone deacetylase (HDAC) inhibitor, and its antiproliferative effects on non‐small cell lung cancer cells have been shown __in vitro__. However, there have been no reports concerning the effects on small‐cell lung cancer (SCLC). We have recently demonstrated that t