Transgenic expression of cholesterol 7α-
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Tiangang Li; Erika Owsley; Michelle Matozel; Peter Hsu; Colleen M. Novak; John Y
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Article
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2010
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John Wiley and Sons
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English
⚖ 837 KB
Cholesterol 7a-hydroxylase (CYP7A1) is the rate-limiting enzyme in the bile acid biosynthetic pathway that converts cholesterol into bile acids in the liver. Recent studies have shown that bile acids may play an important role in maintaining lipid, glucose, and energy homeostasis. However, the role