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Effects of hepatitis B virus X protein on human telomerase reverse transcriptase expression and activity in hepatoma cells

✍ Scribed by Xiaodong Zhang; Nan Dong; Hang Zhang; Jiacong You; Honghui Wang; Lihong Ye

Book ID: 113772589
Publisher: Elsevier Science
Year: 2005
Tongue: English
Weight: 258 KB
Volume: 145
Category: Article
ISSN: 1532-6543
DOI: 10.1016/j.lab.2004.11.018

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## Abstract Normal somatic cells possess a finite life span owing to replicative senescence. Telomerase functions as a potential regulator of senescence in various cells. Expression level of human telomerase reverse transcriptase (hTERT) is correlated with telomerase activity and cellular immortali