Heparin augments osteoclast resorption-s
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K. Fuller; T. J. Chambers; A. C. Gallagher
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Article
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1991
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John Wiley and Sons
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English
โ 778 KB
Increased numbers of mast cells are commonly seen at sites of increased bone resorption and in osteoporosis. Long-term administration of heparin, a major component of mast cell granules, causes osteoporosis. We therefore tested the effect of heparin on bone resorption by osteoclasts disaggregated fr