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Effects of growth hormone and thyroxine on pituitary and testicular function in two types of hereditary dwarf mice

✍ Scribed by Doherty, P. C. ;Bartke, A. ;Dalterio, S. ;Shuster, L. ;Roberson, C.


Publisher
John Wiley and Sons
Year
1980
Tongue
English
Weight
509 KB
Volume
214
Category
Article
ISSN
0022-104X

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✦ Synopsis


Hereditary dwarf mice are growth hormone (GH)-and prolactin (PRLI-deficient and hypothyroid. Administration of PRL, GH, or thyroxine (T,) can induce fertility in male dwarf mice. The mechanism of action of PRL appears to involve stimulation of FSH release, increased ability of the testes to bind LH, and increased production of testosterone (T) and spermatozoa. To obtain some informa-


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