## Abstract The binding of luteinizing hormone (LH) to testicular homogenates increased gradually in mice from 15 to 60 days of age, while the level at 90 days was almost the same as that at 60 days. The plasma concentration of prolactin (PRL) increased significantly from 15 to 40 days and thereaft
Effects of growth hormone and thyroxine on pituitary and testicular function in two types of hereditary dwarf mice
β Scribed by Doherty, P. C. ;Bartke, A. ;Dalterio, S. ;Shuster, L. ;Roberson, C.
- Publisher
- John Wiley and Sons
- Year
- 1980
- Tongue
- English
- Weight
- 509 KB
- Volume
- 214
- Category
- Article
- ISSN
- 0022-104X
No coin nor oath required. For personal study only.
β¦ Synopsis
Hereditary dwarf mice are growth hormone (GH)-and prolactin (PRLI-deficient and hypothyroid. Administration of PRL, GH, or thyroxine (T,) can induce fertility in male dwarf mice. The mechanism of action of PRL appears to involve stimulation of FSH release, increased ability of the testes to bind LH, and increased production of testosterone (T) and spermatozoa. To obtain some informa-
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