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Effects of grapefruit juice on the absorption of levothyroxine

โœ Scribed by Jari J. Lilja; Kalevi Laitinen; Pertti J. Neuvonen

Book ID
108641383
Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
94 KB
Volume
60
Category
Article
ISSN
0306-5251

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โœ John S. Grundy; Lise A. Eliot; Ken M. Kulmatycki; Robert T. Foster ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 157 KB ๐Ÿ‘ 2 views

Previous studies with rats indicate that nifedipine undergoes both hepatic and extrahepatic presystemic metabolism after peroral (po) administration, and that its bioavailability is increased and absorption delayed by concomitant administration of grapefruit juice concentrate (GJC). Hence, the effec