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Effects of gossypol on the kidney with special emphasis on potassium (K) excretion

✍ Scribed by C. van Ypersele de Strihou; J.P. Dieu; E. Marbaix


Book ID
115844401
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
257 KB
Volume
37
Category
Article
ISSN
0010-7824

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✍ Gedske Daugaard; Niels Rossing; Mikael RΓΈrth πŸ“‚ Article πŸ“… 1988 πŸ› Springer 🌐 English βš– 500 KB

To investigate the effect of high-dose cisplatin (40 mg/m2 daily for 5 days), 51Cr-EDTA clearance was used as a measure of glomerular filtration rate (GFR). 51Cr-EDTA clearance decreased significantly from 109 +/- 3 ml/min \* 1.73 m2 to 68 +/- 3 ml/min \* 1.73 m2 after three cycles of cisplatin and