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Effects of glycaemia on glucose transport in isolated skeletal muscle from patients with NIDDM: in vitro reversal of muscular insulin resistance

✍ Scribed by J. R. Zierath; D. Galuska; L. A. Nolte; A. Thörne; J. Smedegaard Kristensen; H. Wallberg-Henriksson

Publisher
Springer
Year
1994
Tongue
English
Weight
972 KB
Volume
37
Category
Article
ISSN
0012-186X

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We examined whether insulin resistance, i. e. impaired insulin stimulated glucose uptake in NIDDM patients and their first-degree relatives is associated with alterations in the effect of insulin on the expression of the GLUT-4 gene in skeletal muscle in vivo. Levels of GLUT-4 mRNA and protein were