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Effects of global knockout or over-expression of fibroblast growth factor-2 in osteoblasts on fracture healing in transgenic mice

✍ Scribed by Liping Xiao; Douglas Adams; Liping Wang; Xi Jiang; Marja M. Hurley


Book ID
116320482
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
73 KB
Volume
42
Category
Article
ISSN
8756-3282

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## Abstract Over‐expression of human FGF‐2 cDNA linked to the phosphoglycerate kinase promoter in transgenic (TgFGF2) mice resulted in a dwarf mouse with premature closure of the growth plate and shortening of bone length. This study was designed to further characterize bone structure and remodelin