✦ LIBER ✦

Effects of Genetic Variation in the Novel Organic Cation Transporter, OCTN1, on the Renal Clearance of Gabapentin

✍ Scribed by Urban, TJ; Brown, C; Castro, RA; Shah, N; Mercer, R; Huang, Y; Brett, CM; Burchard, EG; Giacomini, KM

Book ID: 110020128
Publisher: Nature Publishing Group
Year: 2007
Tongue: English
Weight: 144 KB
Volume: 83
Category: Article
ISSN: 0009-9236
DOI: 10.1038/sj.clpt.6100271

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Expression of novel organic cation/carni

Expression of novel organic cation/carnitine transporter (OCTN2) in the mouse pancreas

✍ Saori Kai; Kazumichi Yakushiji; Masamichi Yamauchi; Chizuru Ito; Masamichi Kuwaj 📂 Article 📅 2005 🏛 Elsevier Science 🌐 English ⚖ 360 KB

Effect of Genetic Variation in the Organ

Effect of Genetic Variation in the Organic Cation Transporter 1, OCT1, on Metformin Pharmacokinetics

✍ Shu, Y; Brown, C; Castro, RA; Shi, RJ; Lin, ET; Owen, RP; Sheardown, SA; Yue, L; 📂 Article 📅 2007 🏛 Nature Publishing Group 🌐 English ⚖ 184 KB

The Effects of Genetic Polymorphisms in

The Effects of Genetic Polymorphisms in the Organic Cation Transporters OCT1, OCT2, and OCT3 on the Renal Clearance of Metformin

✍ Tzvetkov, M V; Vormfelde, S V; Balen, D; Meineke, I; Schmidt, T; Sehrt, D; Sabol 📂 Article 📅 2009 🏛 Nature Publishing Group 🌐 English ⚖ 328 KB

Functional characterization of human org

Functional characterization of human organic cation transporter OCTN1 single nucleotide polymorphisms in the Japanese population

✍ Yuki Kawasaki; Yukio Kato; Yoshimichi Sai; Akira Tsuji 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 139 KB 👁 1 views

The organic cation transporter OCTN1 (SLC22A4) is expressed ubiquitously, with strong expression in kidney, trachea, bone marrow, and fetal liver, and it mediates transport of organic cations in a pH-dependent manner. Recent studies have identified single nucleotide polymorphisms (SNPs) of OCTN1 in

The antioxidant L-ergothioneine modulate

The antioxidant L-ergothioneine modulates the expression of its receptor, the organic cation transporter OCTN1, in skin cells and tissue

📂 Article 📅 2009 🏛 Elsevier Science 🌐 English ⚖ 45 KB

Effects of inorganic divalent cations on

Effects of inorganic divalent cations on the renal basolateral transport system for organic anions

✍ Helge Hohage; Fritz Matzkies; Ulrike Mergelsberg; Marina Löhr; Joachim Greven 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 65 KB 👁 2 views

Recent work demonstrated that the heavy metal ion Cd2+ increases the transport of p-aminohippuric acid (PAH) across the basolateral membrane of microdissected non-perfused rabbit kidney S2 proximal tubule segments. Usually, such ions induce damage of various renal transport systems, therefore the ef