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Effects of genetic polymorphisms of MDR1, FMO3 and CYP1A2 on susceptibility to colorectal cancer in Koreans

✍ Scribed by Sun-Young Bae; Sun-Keun Choi; Kyung-Rae Kim; Chang-Shin Park; Sung-Keun Lee; Hyung-Keun Roh; Dong-Woon Shin; Jae-Eun Pie; Ze-Hong Woo; Ju-Hee Kang

Book ID
108583678
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
137 KB
Volume
97
Category
Article
ISSN
1347-9032

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## Abstract Cytochrome P‐450 CYP1A1 is involved in the metabolism of polycyclic aromatic hydrocarbons (PAHs) that are derived from meat intake and tobacco smoking. Expression of the __CYP1A1__ gene is induced by compounds present in cruciferous vegetables. The glutathione __S__‐transferases play a