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Effects of genetic background and environmental novelty on wheel running as a rewarding behaviour in mice

✍ Scribed by Leonie de Visser; Ruud van den Bos; Astrid K. Stoker; Martien J.H. Kas; Berry M. Spruijt

Book ID
116284494
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
437 KB
Volume
177
Category
Article
ISSN
0166-4328

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## Abstract Mice with disrupted germline __p53__ alleles have been engineered by us and others and have been shown to have enhanced susceptibility to spontaneous tumors of various types. We monitored a large number of __p53__‐deficient mice(__p53__+/βˆ’ and __p53__βˆ’/βˆ’) and their wild‐type littermates