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Effects of Gabapentin on Calcium Transients in Neurons of the Rat Dorsal Root Ganglia

โœ Scribed by S. V. Romanenko; P. G. Kostyuk; E. P. Kostyuk


Publisher
Springer US
Year
2008
Tongue
English
Weight
432 KB
Volume
40
Category
Article
ISSN
0090-2977

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Whole-cell patch-clamp experiments were performed with neurons cultured from rat dorsal root ganglia (DRG). Two types of Na+ currents were identified on the basis of sensitivity to tetrodotoxin. One type was blocked by 0.1 nM tetrodotoxin, while the other type was insensitive to 10 microM tetrodotox