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Effects of FXR in foam-cell formation and atherosclerosis development

โœ Scribed by Grace L. Guo; Silvia Santamarina-Fojo; Taro E. Akiyama; Marcelo J.A. Amar; Beverly J. Paigen; Bryan Brewer Jr.; Frank J. Gonzalez


Book ID
116273155
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
765 KB
Volume
1761
Category
Article
ISSN
1388-1981

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FOAM CELL APOPTOSIS AND THE DEVELOPMENT
โœ HEGYI, LASZLO; SKEPPER, JEREMY N.; CARY, NAT R. B.; MITCHINSON, MALCOLM J. ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 800 KB

A characteristic feature of the advanced atherosclerotic lesion is the acellular lipid core, which appears to result at least partly from the death of macrophage foam cells. This study shows that foam cell death at the edge of the lipid core includes both necrosis and apoptosis and that remnants of