Effects of frontal brain electroshock stimulation on eeg activity and memory in rats: Relationship to ECS-produced retrograde amnesia
✍ Scribed by Zornetzer, Steven ;McGaugh, James L.
- Publisher
- John Wiley and Sons
- Year
- 1969
- Tongue
- English
- Weight
- 1017 KB
- Volume
- 1
- Category
- Article
- ISSN
- 0022-3034
No coin nor oath required. For personal study only.
✦ Synopsis
Electroencephalographic changes occurring in rat brain following frontal cortex stimulation in non-lesioned rats and in rats with bilateral lesions in the region of amygdala were investigated in Experiment I.
Seizure duration and EEG spike frequency varied systematically with current level. The amnesic effects of conventional EGS and frontal cortex stimulation were studied in Experiment 11. Both treatments were highly effective in producing retrograde amnesia for an inhibitory avoidance response. The findings are interpreted as suggesting that the effectiveness of ECS in producing RA varies with the amount of current reaching the brain.