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Effects of food and sucralfate on the pharmacokinetics of naproxen and ketoprofen in humans

✍ Scribed by Gilles Caillé; Patrick du Souich; Jean Guy Besner; Pierre Gervais; Manon Vézina


Book ID
115682626
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
825 KB
Volume
86
Category
Article
ISSN
1555-7162

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Single dose pharmacokinetics of ketoprof
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The effects of sucralfate on the rate and extent of absorption of ketoprofen, indomethacin, and naproxen were investigated in healthy volunteers. Six volunteers each received sucralfate (2 g) half an hour before a ketoprofen (50 mg) capsule, and, on another occasion, a ketoprofen (50mg) capsule alon

Pharmacokinetics of ketoprofen in rats:
✍ Julia H. Satterwhite; F. Douglas Boudinot 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 English ⚖ 682 KB

## Abstract The effects of age and dose on the pharmacokinetics of ketoprofen were evaluated in young adult and senescent male Fischer 344 rats following intravenous administration of 2·5 and 10 mg kg^−1^. Plasma concentrations were measured by HPLC and free ketoprofen determined by equilibrium dia