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Effects of fluoroquinolones on the locomotor activity in rats

✍ Scribed by Renate Thiel; Stefanie Metzner; Christine Gericke; Ute Rahm; Ralf Stahlmann

Publisher
Springer-Verlag
Year
2001
Tongue
English
Weight
123 KB
Volume
75
Category
Article
ISSN
0340-5761

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## Abstract Effects of vigibatrin (saline, 125, 250, or 500 mg/kg i.p.) on spontaneous locomotor activity in Wistar rats were investigated. There was a dose dependent decrease in amount of locomotion for doses up to 250 mg/kg. This decrease was measurable 2–4 hours after injection and still became