Antimetrazol action of flunarizine (5, 10, 20 and 40 mg/kg i.p.) was tested during ontogenesis on male Wistar rats aged 7, 12, 18, 25 and 90 days. The latencies and incidences of jerks, minimal Metrazol seizures and major Metrazol seizures remained unchanged by flunarizine in all age groups. A speci
β¦ LIBER β¦
Effects of flunarizine on spontaneous synaptic currents in rat neocortex
β Scribed by P. T. Golumbek; J. M. Rho; W. J. Spain; J. F. M. van Brederode
- Publisher
- Springer-Verlag
- Year
- 2004
- Tongue
- English
- Weight
- 259 KB
- Volume
- 370
- Category
- Article
- ISSN
- 0028-1298
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Our laboratory has reported previously the characteristics of specific AVP binding to rat hippocampal synaptic membranes (SPM) in the presence of Ni2+ [Costantini MG, Pearlmutter AF: J Biol Chem 259: 11739-11745, 1984]. We extended our investigation to determine the effects of Ni2+, (AVP), and AVP a