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Effects of flunarizine and diltiazem on physical dependence on barbital in rats

✍ Scribed by Tsutomu Suzuki; Hirokazu Mizoguchi; Hideaki Noguchi; Toshio Yoshii; Miwa Misawa


Book ID
113225769
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
767 KB
Volume
45
Category
Article
ISSN
0091-3057

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Effects of flunarizine on Metrazol-induc
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Antimetrazol action of flunarizine (5, 10, 20 and 40 mg/kg i.p.) was tested during ontogenesis on male Wistar rats aged 7, 12, 18, 25 and 90 days. The latencies and incidences of jerks, minimal Metrazol seizures and major Metrazol seizures remained unchanged by flunarizine in all age groups. A speci