Role of glucocorticoids in mediating eff
Role of glucocorticoids in mediating effects of fasting and diabetes on hypothalamic gene expression
โ
Hideo Makimura; Tooru M Mizuno; Fumiko Isoda; Joe Beasley; Jeffrey H Silverstein
๐
Article
๐
2003
๐
BioMed Central
๐
English
โ 751 KB
## Background: Fasting and diabetes are characterized by elevated glucocorticoids and reduced insulin, leptin, elevated hypothalamic agrp and npy mrna, and reduced hypothalamic pomc mrna. although leptin replacement can reverse changes in hypothalamic gene expression associated with fasting and dia