Indolizinsulphones. A class of blockers
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Patrick Bois; Georges Romey; Michel Lazdunski
📂
Article
📅
1991
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Springer
🌐
English
⚖ 636 KB
The alpha 1 subunit of the L-type Ca2+ channel plays a dual role in skeletal muscle. It is essential both for L-type Ca2+ channel activity and for the functioning of the voltage-sensor structure that is situated in the triads as a key element for excitation-contraction coupling. This paper shows, wi