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Effects of etofibrate, clofibrate and nicotinic acid on lipid metabolism in hyperlipidemic rats

✍ Scribed by Priego, J.G.; Maroto, M.L.; Piña, M.; Catalán, R.E.

Book ID
123056254
Publisher
Elsevier Science
Year
1979
Tongue
English
Weight
327 KB
Volume
10
Category
Article
ISSN
0306-3623

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Etofibrate, the ethylene glycol diester of clofibric and nicotinic acids, on intravenous infusion into dogs, has a terminal half-life of 2 min. The intermediate half-esters, the nicotinate and the clofibrate, have respective terminal half-lives of 4.6 and 1.7 rnin and appear fleetingly when etofibra