Expression and regulation of cytochrome
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Edward L. LeCluyse; Ajay Madan; Geraldine Hamilton; Kathy Carroll; Ryan DeHaan;
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Article
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2000
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John Wiley and Sons
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English
⚖ 339 KB
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The aim of this study was to test suitable culture conditions for maintaining normal cellular cytoarchitecture and inducibility of P450 enzymes in primary cultures of human hepatocytes by prototypical inducers. The selectivity and sensitivity of a sandwich culture system were determined by treating