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Effects of estradiol concentration on levels of nuclear estrogen receptors in MCF-7 breast tumor cells

โœ Scribed by Robert S. Umans; Ralph R. Weichselbaum; Carole M. Johnson; John B. Little

Book ID
116004141
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
554 KB
Volume
20
Category
Article
ISSN
0022-4731

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Exposure of MCF-7 cells to single and/or repeated low โฅ-ray doses (0.5 to 8 Gy) resulted in a decrease in the capacity of these cells to concentrate tritiated estradiol ([ 3 H]E 2 ) (reduction of the number of binding sites). The decrease in the [ 3 H]E 2 -binding capacity was higher than the surviv