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Effects of epidermal growth factor on apo B mRNA levels and apo B accumulation in the media of primate hepatocytes in culture

✍ Scribed by William L. Blake; Thomas J. Vidmar; George W. Melchior

Book ID: 117055078
Publisher: Elsevier Science
Year: 1992
Tongue: English
Weight: 345 KB
Volume: 186
Category: Article
ISSN: 0006-291X
DOI: 10.1016/s0006-291x(05)80793-4

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## Abstract We have characterized the effect of the hepatomitogen epidermal growth factor (EGF) on the expression of the cellular protooncogenes c‐Ha‐ras and c‐myc in short‐term (48 hours) primary hepatocyte culture. mRNA concentrations of both protooncogenes increased dramatically in nonproliferat