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Effects of endothelin-1 and nitric oxide on proliferation of cultured guinea pig bronchial smooth muscle cells

✍ Scribed by Yasuo Kizawa; Nozomi Ohuchi; Kiyoshige Saito; Tadashi Kusama; Hajime Murakami

Book ID
117794179
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
137 KB
Volume
128
Category
Article
ISSN
1532-0456

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Two important mediators of endothelium-dependent regulation of vascular smooth muscle tone and proliferation are nitric oxide (NO) and endothelin (ET-1). An imbalance between NO and ET-1 may contribute to the alterations in vascular tone characteristic of cardiovascular disease. The objective of thi