Effects of mechanical load on the expres
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Reiko Kitamura; Kotaro Tanimoto; Yuki Tanne; Takashi Kamiya; Yu-Ching Huang; Nob
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Article
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2010
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John Wiley and Sons
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English
β 240 KB
## Abstract Hyaluronan (HA) has lubricating and buffering functions in joints. Mechanical load is a regulatory factor of HA metabolism in joints, and HA synthesis by synovial membrane cells is modulated by mechanical load. However, the effects of mechanical load on HA catabolism by hyaluronidase (H