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Effects of EGF and thrombin on inositol-containing phospholipids of cultured fibroblasts: Stimulation of phosphatidylinositol synthesis by thrombin but not EGF

✍ Scribed by Daniel M. Raben; Dennis D. Cunningham


Publisher
John Wiley and Sons
Year
1985
Tongue
English
Weight
855 KB
Volume
125
Category
Article
ISSN
0021-9541

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✦ Synopsis


The effects of growth factors on inositol-containing phospholipids were investigated to test the hypothesis that alterations in their metabolism are involved in mitogenic stimulation. Thrombin and EGF stimulated comparable increases in the synthesis (30-50%) and degradation (2040%) of phosphatidylinositol 4-