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Effects of echo time on diffusion quantification of brain white matter at 1.5T and 3.0T

✍ Scribed by Wen Qin; Chun Shui Yu; Fan Zhang; Xiang Ying Du; Heng Jiang; Yu Xia Yan; Kun Cheng Li

Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
265 KB
Volume
61
Category
Article
ISSN
0740-3194

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✦ Synopsis

Abstract

The aim was to investigate the effects of echo time (TE) on diffusion quantification of brain white matter. Seven rhesus monkeys (all males; age, 4–6 years; weight, 5–7 kg) underwent diffusion tensor imaging (DTI) with a series of TEs in 1.5T and 3.0T MR scanners. The mean diffusivity (MD), fractional anisotropy (FA), primary (λ~1~), and transverse eigenvalues (λ~23~) were measured in a region of interest at the bilateral internal capsule. Pearson correlation showed that the FA and λ~1~ increased and λ~23~ decreased with TE both at 1.5T and 3.0T except for the MD. Repeated measurement analysis of variance (ANOVA) also showed significantly higher FA and lower MD and λ~23~ at 3.0T than those at 1.5T (P < 0.01), but no statistical differences were found in λ~1~ between these two field strengths (P = 0.709). These findings implied that TE and field strength might influence diffusion quantification in brain white matter. Magn Reson Med, 2009. © 2009 Wiley‐Liss, Inc.

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