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Effects of drug-metabolizing enzyme inducers on cephaoloridine toxicity in fischer 344 rats

โœ Scribed by Chao-Hen Kuo; Jerry B. Hook


Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
480 KB
Volume
24
Category
Article
ISSN
0300-483X

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โœ Thomas B. Leonard; D. Gwyn Morgan; John G. Dent ๐Ÿ“‚ Article ๐Ÿ“… 1985 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 970 KB

Cimetidine has been shown to protect against acetaminophen-mediated hepatotoxicity in both rats and mice. In contrast to cimetidine, ranitidine recently has been determined to potentiate the hepatotoxic action of acetaminophen in Fischer 344 rats. The present studies were designed to characterize th