Ranitidine-acetaminophen interaction: Ef
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Thomas B. Leonard; D. Gwyn Morgan; John G. Dent
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Article
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1985
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John Wiley and Sons
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English
โ 970 KB
Cimetidine has been shown to protect against acetaminophen-mediated hepatotoxicity in both rats and mice. In contrast to cimetidine, ranitidine recently has been determined to potentiate the hepatotoxic action of acetaminophen in Fischer 344 rats. The present studies were designed to characterize th