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Effects of dopamine receptor D4 variation on alcohol and tobacco use and on novelty seeking: Multivariate linkage and association analysis

✍ Scribed by Luciano, Michelle ;Zhu, G. ;Kirk, K.M. ;Whitfield, J.B. ;Butler, R. ;Heath, A.C. ;Madden, P.A.F. ;Martin, N.G.


Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
109 KB
Volume
124B
Category
Article
ISSN
0148-7299

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A dysfunction of dopaminergic neurotansmission has been implicated in alcoholseeking behavior. Recently, a significant association between the seven-repeat allele (DRD4\*7R) of a 16 amino acid motif in the third exon of the dopamine D4 receptor gene (DRD4) and the personality trait of novelty seekin