Effects of dopamine agonists and antagonists on PCP-induced stereotyped behaviour and social isolation in the rat social interaction test

Lack of effects of 5HT3receptor antagoni

Lack of effects of 5HT3receptor antagonists in the social interaction and elevated plus-maze tests of anxiety in the rat

✍ Sandra E. File; Amanda L. Johnston 📂 Article 📅 1989 🏛 Springer 🌐 English ⚖ 463 KB

The effects of three 5HT3 receptor antagonists: BRL 43964 (0.1 and 1 mg/kg, oral), GR 38032F (0.1 and 1 mg/kg, oral), and zacopride (0.01, 0.1 and 1 mg/kg, IP) were examined in low light test conditions of the social interaction test. None of the three 5HT3 receptor antagonists had a significant eff