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Effects of DNA methyltransferase 1 inhibition on esophageal squamous cell carcinoma

โœ Scribed by Shu-Lei Zhao; Sheng-Tao Zhu; Xiaowen Hao; Peng Li; Shu-Tian Zhang

Book ID
108982432
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
869 KB
Volume
24
Category
Article
ISSN
1120-8694

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Frequent somatic mutations of mitochondrial DNA in esophageal squamous cell carcinoma
โœ Hiroshi Kumimoto; Yoshihiro Yamane; Yoshio Nishimoto; Hiroko Fukami; Masayuki Sh ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 70 KB

## Abstract Recent studies of various cancers, such as those of the breast, head and neck, bladder and lung, reported that 46โ€“64% of somatic mutations in the Dโ€loop region of mitochondrial DNA (mtDNA) are observed. However, in esophageal cancer, only a low rate (5%) of somatic mutations has so far