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Effects of disulfiram on hepatic P450IIE1, other microsomal enzymes, and hepatotoxicity in rats

✍ Scribed by John F. Brady; Fang Xiao; Mong-Heng Wang; Yan Li; Shu M. Ning; Jeanne M. Gapac; Chung S. Yang

Book ID
113207615
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
851 KB
Volume
108
Category
Article
ISSN
0041-008X

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The objective of this stud)' was to investigate ~f the altered 2El drug metabolism capaci~' in rats is due to effi, cts of dietar), zinc deficiency on the expression of hepatic microsomal P450 2El in rats. Rats were given free access to either a zinc-adequate diet or a zinc-deficient diet for 3 week