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Effects of diffusional barriers on the extent of presystemic and systemic intestinal elimination of drugs

โœ Scribed by Younggil Kwon


Book ID
105671689
Publisher
Springer
Year
1997
Tongue
English
Weight
401 KB
Volume
20
Category
Article
ISSN
0253-6269

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Modern drug discovery chemical libraries contain a large number of molecular entities exhibiting low aqueous solubility, often necessitating the inclusion of solubilizing agents in preclinical models of absorption or metabolism. The objective of the present study was to investigate the effects of se