✦ LIBER ✦
Effects of diets containing seeds of Garcinia kola (Heckel) on gastric acidity and experimental ulceration in rats
✍ Scribed by G. F. Ibironke; S. B. Olaleye; O. Balogun; A. Aremu
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 74 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0951-418X
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✦ Synopsis
The antiulcerogenic and gastric acid lowering effects of Garcinia kola (Heckel) seeds were investigated in male albino rats. The animals were fed for 2 weeks on normal rat diets but specially composed to contain 25%, 50% and 75% by weight of G. kola. It was observed that G. kola produced a dose-dependent inhibition of gastric acid secretion and indomethacin-induced ulceration. We suggest that this might be due to its acid-lowering effect and increased mucus production among other factors yet to be determined.