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Effects of diethylenetriamine dihydrochloride following 13 weeks of dietary dosing in fischer 344 rats

✍ Scribed by H.-W Leung; J.P van Miller


Book ID
117450594
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
543 KB
Volume
35
Category
Article
ISSN
0278-6915

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The metabolism and disposition of diethylenetriamine trihydrochloride (DETAβ€’3HCl) were studied with regard to route of administration and dosage effects. Male Fischer 344 rats were administered 50 or 500 mg kg -1 of [1,2-14 C]-DETAβ€’3HCl orally or endotracheally, and the fate of the 14 C-radioactivit