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Effects of denaturation and methylation on the degradation of proteins in cultured hepatoma cells and in reticulocyte cell-free systems

โœ Scribed by Revital KATZNELSON; Richard G. KULKA


Book ID
115122882
Publisher
John Wiley and Sons
Year
1985
Tongue
English
Weight
693 KB
Volume
146
Category
Article
ISSN
1432-1327

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A wide variety of agents are shown to mimic insulin action and inhibit rates of intracellular protein degradation in H35 hepatoma cells. For oxidizing agents such as NaNO2, H2O2 and oxidized glutathione, inhibition of protein breakdown is reversed by adding catalase. Phenylhydrazine behaves like an