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Effects of Decreasing Mitochondrial Volume on the Regulation of the Permeability Transition Pore

✍ Scribed by Véronique Nogueira; Anne Devin; Ludivine Walter; Michel Rigoulet; Xavier Leverve; Eric Fontaine

Publisher
Springer US
Year
2005
Tongue
English
Weight
141 KB
Volume
37
Category
Article
ISSN
0145-479X

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Mitochondria of higher cells contain a channel, the permeability transition pore (PTP), that, when open, increases the permeability of the inner membrane to ions and small molecules. The PTP may be of importance in cellular calcium homeostasis and in the execution of programmed cell death, and the d