Effects of D-600 on sodium current in squid axons
β Scribed by John R. Clay; Alvin Shrier
- Publisher
- Springer
- Year
- 1984
- Tongue
- English
- Weight
- 367 KB
- Volume
- 79
- Category
- Article
- ISSN
- 0022-2631
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Asymmetric displacement currents, Ig, were measured in squid axons at different hydrostatic pressures, P, up to 60 MPa. Potassium and sodium currents were abolished by intracellular Cs+ and TEA+, by extracellular Tetrodotoxin (TTX), and by Na+ substitution with Tris+. The time course of Ig became pr
The effect of bath application of several short chain N-alcohols on voltage-dependent potassium conductance has been studied in intact giant axons of Loligo forbesi under voltage-clamp conditions. All tested alcohols (methanol, ethanol, propanol, butanol, heptanol and octanol) were found to depress