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Effects of Cα-methyl substitution on the conformation of linear GnRH antagonist analogs

✍ Scribed by LIFF, MARK I. ;KOPPLE, KENNETH D. ;TIAN, ZHENPING ;ROESKE, ROGER W.


Book ID
115099668
Publisher
Wiley (Blackwell Publishing)
Year
2009
Tongue
English
Weight
455 KB
Volume
43
Category
Article
ISSN
0367-8377

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The preferred conformations of C"-methyl phenylglycine, C"-methyl phenylalanine, and C"-methyl homophenylalanine residues, as determined in model peptides (including homopeptides) by Fourier transform ir absorption, 'H-nmr, CD, and x-ray diffraction techniques, are compared with the aim of investiga