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Effects of cyclosporin A on growth and polyamine metabolism of MOLT-4 T-lymphoblastic leukaemia cells

✍ Scribed by McLachlan, G; Thomson, AW; Wallace, HM

Book ID
109836608
Publisher
Nature Publishing Group
Year
1991
Tongue
English
Weight
799 KB
Volume
64
Category
Article
ISSN
0007-0920

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Influence of cyclosporin a on growth of
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Our objective was to examine the effect of cyclosporin A (CsA; 25 or 12.5 mg/kg) on growth of an acute (Roser) T-cell leukaemia in male PVG rats. The leukaemic blasts were shown (by immunocytochemical analysis) to have a mature, T-helpercell phenotype, Le., OX-I9 (CD5)\*, W3/25 (CD4)+, OX44+, MHC-cl