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Effects of Curvature and Composition on α-Synuclein Binding to Lipid Vesicles

✍ Scribed by Middleton, Elizabeth R.; Rhoades, Elizabeth


Book ID
119207480
Publisher
Biophysical Society
Year
2010
Tongue
English
Weight
441 KB
Volume
99
Category
Article
ISSN
0006-3495

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The 11-mer repeats of human α-synuclein
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## Abstract α‐Synuclein is a protein abundant in presynaptic terminals in the brain. The N‐terminal region of the sequence contains an imperfect 11‐residue periodicity also found in A‐class apolipoproteins and able to fold into an amphipathic helix. Here, the ability of three fragments of the prote