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Effects of Co2+ on the erythromycin biosynthesis

✍ Scribed by Du, Wen ;Chen, Changhua


Book ID
107475795
Publisher
Higher Education Press and Springer
Year
2007
Tongue
English
Weight
343 KB
Volume
1
Category
Article
ISSN
1673-7369

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Erythromycin biosynthesis: Exploiting th
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DEBS 1 + TE is a recombinant modular polyketide synthase (PKS) in which the first two biosynthetic modules of the 6-deoxyerythronolide B synthase are linked to the thioesterase domain normally found at the C-terminus of DEBS 3. Incubation of DEBS 1 + TE with propionyl-CoA, methylamalonyl-CoA, and NA