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Effects of cis-diamminedichloroplatinum (II) upon haemopoietic progenitors and the haemopoietic microenvironment in mice

✍ Scribed by Peter G. J. Nikkels; Johannes P. De Jong; Rob E. Ploemacher


Book ID
114711450
Publisher
John Wiley and Sons
Year
1988
Tongue
English
Weight
568 KB
Volume
68
Category
Article
ISSN
0007-1048

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## Abstract The synergistic effect of local hyperthermia (LHT) with intratumor injection (i.t.) of cis‐diamminedichloroplatinum (II) (DDP) was studied using a rodent model with implanted B16 melanoma tumors. The hindfoot of the C57BL/6 mouse bearing the tumor was placed in a water bath at 42.5 Β± 0.