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Effects of cigarette smoke on degranulation and NO production by mast cells and epithelial cells

✍ Scribed by Xiu M Wei; Henry S Kim; Rakesh K Kumar; Gavin J Heywood; John E Hunt; H Patrick McNeil; Paul S Thomas


Book ID
119893830
Publisher
BioMed Central
Year
2005
Tongue
English
Weight
620 KB
Volume
6
Category
Article
ISSN
1465-9921

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Endothelin-1 (ET-1), originally described as a vasoconstrictor, is now known to be involved in pathogenesis of various disorders including vascular, inflammatory, and fibrotic diseases. Recent studies suggest that mast cells are also involved in the same pathological conditions. In this study, we te