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Effects of chronic protein malnutrition and nutritional repletion on lidocaine pharmacokinetics in rats

✍ Scribed by Petit, J.; Moore, N.; Hecketsweiler, B.; Kaeffer, N.; Lerebours, E.; Oksenhendler, G.; Colin, R.

Book ID
123103307
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
105 KB
Volume
11
Category
Article
ISSN
0261-5614

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Effects of cysteine on the pharmacokinetics of oltipraz were investigated after iv (10 mg/kg) and oral (30 mg/kg) administration to male control, protein-calorie malnutrition (PCM), and PCM with oral cysteine supplementation (PCMC) rats. It was reported that oltipraz was mainly metabolized via hepat