Effects of chronic overexpression of interleukin-1 receptor antagonist in a model of permanent focal cerebral ischemia in mouse
β Scribed by Mircea Oprica; Anne-Marie Dam; Johan Lundkvist; Kerstin Iverfeldt; Bengt Winblad; Tamas Bartfai; Marianne Schultzberg
- Publisher
- Springer-Verlag
- Year
- 2004
- Tongue
- English
- Weight
- 790 KB
- Volume
- 108
- Category
- Article
- ISSN
- 0001-6322
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Conditions associated with systemic infection, such as endotoxinemia, are known to increase the levels of proinflammatory cytokines such as interleukin (IL)-1 in the central nervous system. Systemic infection has been shown to be a common preexisting condition in patients with stroke. To examine a p
## Abstract Asiatic acid, a triterpenoid derivative from __Centella asiatica__, has shown biological effects such as antioxidant, antiinflammatory, and protection against glutamateβ or Ξ²βamyloidβinduced neurotoxicity. We investigated the neuroprotective effect of asiatic acid in a mouse model of pe
## Abstract We have previously reported that prostaglandin A~1~ (PGA~1~) reduces infarct size in rodent models of focal ischemia. This study seeks to elucidate the possible molecular mechanisms underlying PGA~1~'s neuroprotective effects against ischemic injury. Rats were subjected to permanent mid